A new anti-mesothelin antibody targets selectively the membrane-associated form

Mesothelin is a glycosylphosphatidylinositol (GPI)-anchored membrane protein that shows promise as a target for antibody-directed cancer therapy. High levels of soluble forms of the antigen represent a barrier to directing therapy to cellular targets. The ability to develop antibodies that can selec...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Asgarov, Kamal, Balland, Jeremy, Tirole, Charline, Bouard, Adeline, Mougey, Virginie, Ramos, Diana, Barroso, António, Zangiacomi, Vincent, Jary, Marine, Kim, Stefano, Gonzalez-Pajuelo, Maria, Royer, Bernard, de Haard, Hans, Clark, Andy, Wijdenes, John, Borg, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384705/
https://ncbi.nlm.nih.gov/pubmed/28353419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1288770
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