A multi-functional PEGylated gold(iii) compound: potent anti-cancer properties and self-assembly into nanostructures for drug co-delivery

Gold(iii) porphyrin–PEG conjugates [Au(TPP–COO–PEG(5000)–OCH(3))]Cl (1) and [Au(TPP–CONH–PEG(5000)–OCH(3))]Cl (2) have been synthesized and characterized. Based on the amphiphilic character of the conjugates, they were found to undergo self-assembly into nanostructures with size 120–200 nm and this...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Chung, Clive Yik-Sham, Fung, Sin-Ki, Tong, Ka-Chung, Wan, Pui-Ki, Lok, Chun-Nam, Huang, Yanyu, Chen, Tianfeng, Che, Chi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384453/
https://ncbi.nlm.nih.gov/pubmed/28451309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03210a
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