Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer’s disease

Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is linked to oxidative stress, altered amyloid precursor protein (APP) proteolysis, tau hyperphosphorylation and the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles (NFT). A growing body of evidence suggests that...

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Publicado no:Heliyon
Main Authors: Sawmiller, Darrell, Li, Song, Mori, Takashi, Habib, Ahsan, Rongo, David, Delic, Vedad, Bradshaw, Patrick C., Shytle, R. Douglas, Sanberg, Cyndy, Bickford, Paula, Tan, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384415/
https://ncbi.nlm.nih.gov/pubmed/28413833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00279
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