Human papilloma virus load and PD-1/PD-L1, CD8(+) and FOXP3 in anal cancer patients treated with chemoradiotherapy: Rationale for immunotherapy

We examined the prognostic role of immune markers programmed cell death protein-1 (PD-1) and its ligand (PD-L1), CD8(+) tumor-infiltrating lymphocytes (TILs), FOXP3+ Tregs and phosphorylated Caspase-8 (T273) in patients with anal squamous cell cancer (ASCC) treated with standard chemoradiotherapy (C...

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Veröffentlicht in:Oncoimmunology
Hauptverfasser: Balermpas, Panagiotis, Martin, Daniel, Wieland, Ulrike, Rave-Fränk, Margret, Strebhardt, Klaus, Rödel, Claus, Fokas, Emmanouil, Rödel, Franz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384387/
https://ncbi.nlm.nih.gov/pubmed/28405521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1288331
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