The immune molecular landscape of the B7 and TNFR immunoregulatory ligand–receptor families in head and neck cancer: A comprehensive overview and the immunotherapeutic implications

The B7 family and tumor necrosis factor receptor (TNFR) superfamily play a vital role in the T-cell co-stimulatory and co-inhibitory pathways, regulating T-cell activation, tolerance, and exhaustion; therapeutic modulation of these pathways is translated into effective new cancer treatments. Better...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Chen, Yu-Pei, Zhang, Jian, Wang, Ya-Qin, Liu, Na, He, Qing-Mei, Yang, Xiao-Jing, Sun, Ying, Ma, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384366/
https://ncbi.nlm.nih.gov/pubmed/28405520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1288329
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