Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity

Exploiting gut mucosal immunity to design new antitumor vaccination strategy remains unexplored. Tumor cell-derived microparticles (T-MP) are natural biomaterials that are capable of delivering tumor antigens and innate signals to dendritic cells (DC) for tumor-specific T cell immunity. Here, we sho...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Dong, Wenqian, Zhang, Huafeng, Yin, Xiaonan, Liu, Yuying, Chen, Degao, Liang, Xiaoyu, Jin, Xun, Lv, Jiadi, Ma, Jingwei, Tang, Ke, Hu, Zhuowei, Qin, Xiaofeng, Huang, Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384362/
https://ncbi.nlm.nih.gov/pubmed/28405506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1282589
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