Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis

The platelet-derived growth factor receptor alpha (PDGFRα) exhibits divergent effects in skeletal muscle. At physiological levels, signaling through this receptor promotes muscle development in growing embryos and proper angiogenesis in regenerating adult muscle.(1,2) However, both increased PDGF li...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Mueller, Alisa A., van Velthoven, Cindy T., Fukumoto, Kathryn D., Cheung, Tom H., Rando, Thomas A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384334/
https://ncbi.nlm.nih.gov/pubmed/27894125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20160
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