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Primate autoimmune disease models; lost for translation?

Replacement, reduction and refinement (the 3R's) are the leading principles in translational research with animals. To be useful a model should also be clinically Relevant (the 4th R). Work in a non-human primate model of multiple sclerosis, the experimental autoimmune encephalomyelitis model,...

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Bibliografiske detaljer
Udgivet i:Clin Transl Immunology
Hovedforfatter: 't Hart, Bert A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384286/
https://ncbi.nlm.nih.gov/pubmed/28435673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.82
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