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Design and Synthesis of Near-Infrared Peptide for in Vivo Molecular Imaging of HER2

We report the development, characterization, and validation of a peptide specific for the extracellular domain of HER2. This probe chemistry was developed for molecular imaging by using a structural model to select an optimal combination of amino acids that maximize the likelihood for unique hydroph...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Joshi, Bishnu P., Zhou, Juan, Pant, Asha, Duan, Xiyu, Zhou, Quan, Kuick, Rork, Owens, Scott R., Appelman, Henry, Wang, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384256/
https://ncbi.nlm.nih.gov/pubmed/26709709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00565
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