Treating Cancer by Targeting Telomeres and Telomerase

Telomerase is expressed in more than 85% of cancer cells. Tumor cells with metastatic potential may have a high telomerase activity, allowing cells to escape from the inhibition of cell proliferation due to shortened telomeres. Human telomerase primarily consists of two main components: hTERT, a cat...

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Bibliographic Details
Published in:Antioxidants (Basel)
Main Authors: Ivancich, Marko, Schrank, Zachary, Wojdyla, Luke, Leviskas, Brandon, Kuckovic, Adijan, Sanjali, Ankita, Puri, Neelu
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384178/
https://ncbi.nlm.nih.gov/pubmed/28218725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox6010015
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