Early-stage Type 2 Diabetes Mellitus Impairs Erectile Function and Neurite Outgrowth From the Major Pelvic Ganglion and Downregulates the Gene Expression of Neurotrophic Factors

OBJECTIVE: To assess neurite sprouting and gene expression of neurotrophic factors, nerve markers, and apoptosis in the major pelvic ganglia (MPGs) of rats with type 2 diabetes mellitus (T2DM) as it relates to erectile function. MATERIALS AND METHODS: Male rats were fed high-fat diet for 2 weeks fol...

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Veröffentlicht in:Urology
Hauptverfasser: Matsui, Hotaka, Musicki, Biljana, Sopko, Nikolai A., Liu, Xiaopu, Hurley, Paula J., Burnett, Arthur L., Bivalacqua, Trinity J., Hannan, Johanna L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384100/
https://ncbi.nlm.nih.gov/pubmed/27639791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2016.08.045
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