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Evolving modular genetic regulatory networks with a recursive, top-down approach

Being able to design genetic regulatory networks (GRNs) to achieve a desired cellular function is one of the main goals of synthetic biology. However, determining minimal GRNs that produce desired time-series behaviors is non-trivial. In this paper, we propose a ‘top-down’ approach to evolving small...

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Bibliographic Details
Published in:Syst Synth Biol
Main Authors: Garcia-Bernardo, Javier, Eppstein, Margaret J.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383792/
https://ncbi.nlm.nih.gov/pubmed/28392850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11693-015-9179-5
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