Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons

Recent advances suggest that in vivo reprogramming of endogenous cell populations provides a viable alternative for neuron replacement. Astrocytes and oligodendrocyte precursor cells can be induced to transdifferentiate into neurons in the CNS, but, in these instances, reprogramming requires either...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: Weinberg, Marc S., Criswell, Hugh E., Powell, Sara K., Bhatt, Aadra P., McCown, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383550/
https://ncbi.nlm.nih.gov/pubmed/28202388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.01.016
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