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Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?

Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently reported role of SEC62 as an autophagy receptor that controls endoplasmic reticulum (ER) size and function might open new scenarios for understanding the phenotypes and treat SEC62(hi...

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Publicat a:Mol Cell Oncol
Autors principals: Bergmann, Timothy J., Fumagalli, Fiorenza, Loi, Marisa, Molinari, Maurizio
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383369/
https://ncbi.nlm.nih.gov/pubmed/28401179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1264351
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