Immune response of rats vaccinated orally with various plant-expressed recombinant cysteine proteinase constructs when challenged with Fasciola hepatica metacercariae

BACKGROUND: Cysteine proteinases of Fasciola hepatica are important candidates for vaccine antigens because of their role in fluke biology and host-parasite relationships. In our previous experiments, we found that a recombinant cysteine proteinase cloned from adult F. hepatica (CPFhW) can protect r...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Kesik-Brodacka, Malgorzata, Lipiec, Agnieszka, Kozak Ljunggren, Monika, Jedlina, Luiza, Miedzinska, Katarzyna, Mikolajczak, Magdalena, Plucienniczak, Andrzej, Legocki, Andrzej B., Wedrychowicz, Halina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383346/
https://ncbi.nlm.nih.gov/pubmed/28333957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005451
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