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KChIP2 regulates the cardiac Ca(2+) transient and myocyte contractility by targeting ryanodine receptor activity

Pathologic electrical remodeling and attenuated cardiac contractility are featured characteristics of heart failure. Coinciding with these remodeling events is a loss of the K(+) channel interacting protein, KChIP2. While, KChIP2 enhances the expression and stability of the Kv4 family of potassium c...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Nassal, Drew M., Wan, Xiaoping, Liu, Haiyan, Laurita, Kenneth R., Deschênes, Isabelle
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383259/
https://ncbi.nlm.nih.gov/pubmed/28384221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175221
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