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Rab11-FIP1 phosphorylation by MARK2 regulates polarity in MDCK cells

MARK2/Par1b/EMK1, a serine/threonine kinase, is required for correct apical/basolateral membrane polarization in epithelial cells. However, the specific substrates mediating MARK2 action are less well understood. We have now found that MARK2 phosphorylates Rab11-FIP1B/C at serine 234 in a consensus...

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Detalhes bibliográficos
Publicado no:Cell Logist
Main Authors: McRae, Rebecca, Lapierre, Lynne A., Manning, Elizabeth H., Goldenring, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383218/
https://ncbi.nlm.nih.gov/pubmed/28396819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21592799.2016.1271498
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