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Genotype Correlation Analysis Reveals Pathway-Based Functional Disequilibrium and Potential Epistasis in the Human Interactome

Epistasis is thought to be a pervasive part of complex phenotypes due to the dynamics and complexity of biological systems, and a further understanding of epistasis in the context of biological pathways may provide insight into the etiology of complex disease. In this study, we use genotype data fro...

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Detalhes bibliográficos
Publicado no:Appl Evol Comput (2014)
Main Authors: Bush, William S., Haines, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382931/
https://ncbi.nlm.nih.gov/pubmed/28393142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-662-45523-4_72
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