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Lower rate of genomic variation identified in the trans-membrane domain of monoamine sub-class of Human G-Protein Coupled Receptors: The Human GPCR-DB Database

BACKGROUND: We have surveyed, compiled and annotated nucleotide variations in 338 human 7-transmembrane receptors (G-protein coupled receptors). In a sample of 32 chromosomes from a Nordic population, we attempted to determine the allele frequencies of 80 non-synonymous SNPs, and found 20 novel poly...

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Detalhes bibliográficos
Main Authors: Wahlestedt, Claes, Brookes, Anthony J, Mottagui-Tabar, Salim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538281/
https://ncbi.nlm.nih.gov/pubmed/15579207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-5-91
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