Systemic Administration of Induced Neural Stem Cells Regulates Complement Activation in Mouse Closed Head Injury Models

Complement activation plays important roles in the pathogenesis of central nervous system (CNS) diseases. Patients face neurological disorders due to the development of complement activation, which contributes to cell apoptosis, brain edema, blood-brain barrier dysfunction and inflammatory infiltrat...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Gao, Mou, Dong, Qin, Yao, Hui, Lu, Yingzhou, Ji, Xinchao, Zou, Mingming, Yang, Zhijun, Xu, Minhui, Xu, Ruxiang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382667/
https://ncbi.nlm.nih.gov/pubmed/28383046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45989
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