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In vitro generation of mature midbrain-type dopamine neurons by adjusting exogenous Nurr1 and Foxa2 expressions to their physiologic patterns

Developmental information aids stem cell biologists in producing tissue-specific cells. Recapitulation of the developmental profile of a specific cell type in an in vitro stem cell system provides a strategy for manipulating cell-fate choice during the differentiation process. Nurr1 and Foxa2 are po...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Kim, Taeho, Song, Jae-Jin, Puspita, Lesly, Valiulahi, Parvin, Shim, Jae-won, Lee, Sang-Hun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382556/
https://ncbi.nlm.nih.gov/pubmed/28280264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.163
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