Toluene diisocyanate exposure induces airway inflammation of bronchial epithelial cells via the activation of transient receptor potential melastatin 8

Toluene diisocyanate (TDI) is the most important cause of occupational asthma (OA), and various pathogenic mechanisms have been suggested. Of these mechanisms, neurogenic inflammation is an important inducer of airway inflammation. Transient receptor potential melastatin 8 (TRPM8) is a well-establis...

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Udgivet i:Exp Mol Med
Main Authors: Kim, Joo-Hee, Jang, Young-Sook, Jang, Seung-Hun, Jung, Ki-Suck, Kim, Seung-Hyun, Ye, Young-Min, Park, Hae-Sim
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382555/
https://ncbi.nlm.nih.gov/pubmed/28255167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.161
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