Expression of D-Amino Acid Oxidase (DAO/DAAO) and D-Amino Acid Oxidase Activator (DAOA/G72) during Development and Aging in the Human Post-mortem Brain

In the brain, D-amino acid oxidase (DAO/DAAO) mainly oxidizes D-serine, a co-agonist of the N-methyl-D-aspartate (NMDA) receptors. Thus, DAO can regulate the function of NMDA receptors via D-serine breakdown. Furthermore, DAO activator (DAOA)/G72 has been reported as both DAOA and repressor. The co-...

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Bibliografske podrobnosti
izdano v:Front Neuroanat
Main Authors: Jagannath, Vinita, Marinova, Zoya, Monoranu, Camelia-Maria, Walitza, Susanne, Grünblatt, Edna
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Neuroanatomy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382383/
https://ncbi.nlm.nih.gov/pubmed/28428746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2017.00031
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