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Myeloid‐derived suppressor cells mediate tolerance induction in autoimmune disease

In multiple sclerosis (MS) T cells aberrantly recognize self‐peptides of the myelin sheath and attack the central nervous system (CNS). Antigen‐specific peptide immunotherapy, which aims to restore tolerance while avoiding the use of non‐specific immunosuppressive drugs, is a promising approach to c...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Wegner, Anja, Verhagen, Johan, Wraith, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382345/
https://ncbi.nlm.nih.gov/pubmed/28140447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12718
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