Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure

Tumour necrosis factor (TNF) is a ubiquitously expressed cytokine with functions beyond the immune system. In several diseases, the induction of TNF expression in resistance artery smooth muscle cells enhances microvascular myogenic vasoconstriction and perturbs blood flow. This pathological role pr...

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Publicat a:Nat Commun
Autors principals: Kroetsch, Jeffrey T., Levy, Andrew S., Zhang, Hangjun, Aschar-Sobbi, Roozbeh, Lidington, Darcy, Offermanns, Stefan, Nedospasov, Sergei A., Backx, Peter H., Heximer, Scott P., Bolz, Steffen-Sebastian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382284/
https://ncbi.nlm.nih.gov/pubmed/28378814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14805
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