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In vivo inhibition of influenza A virus replication by RNA interference targeting the PB2 subunit via intratracheal delivery
BACKGROUND: Influenza virus infection is a major threat to human health. Small interfering RNA (siRNA) is a promising approach for the prevention and treatment of viral infections. In this study, we constructed a series of DNA vector-based short hairpin RNAs (shRNAs) that target various genes of the...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5381882/ https://ncbi.nlm.nih.gov/pubmed/28380007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174523 |
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