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Rotamer-restricted fluorogenicity of the bis-arsenical ReAsH

Fluorogenic dyes such as FlAsH and ReAsH are used widely to localize, monitor, and characterize proteins and their assemblies in live cells. These bis-arsenical dyes can become fluorescent when bound to a protein containing four proximal Cys thiols – a tetracysteine (Cys(4)) motif. Yet the mechanism...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Walker, Allison S., Rablen, Paul X., Schepartz, Alanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381806/
https://ncbi.nlm.nih.gov/pubmed/27163487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03422
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