Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial

AIMS: Cardiopoietic cells, produced through cardiogenic conditioning of patients’ mesenchymal stem cells, have shown preliminary efficacy. The Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial aimed to validate cardiopoiesis-based biotherapy in a larger heart failure cohort...

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Pubblicato in:Eur Heart J
Autori principali: Bartunek, Jozef, Terzic, Andre, Davison, Beth A., Filippatos, Gerasimos S., Radovanovic, Slavica, Beleslin, Branko, Merkely, Bela, Musialek, Piotr, Wojakowski, Wojciech, Andreka, Peter, Horvath, Ivan G., Katz, Amos, Dolatabadi, Dariouch, El Nakadi, Badih, Arandjelovic, Aleksandra, Edes, Istvan, Seferovic, Petar M., Obradovic, Slobodan, Vanderheyden, Marc, Jagic, Nikola, Petrov, Ivo, Atar, Shaul, Halabi, Majdi, Gelev, Valeri L., Shochat, Michael K., Kasprzak, Jaroslaw D., Sanz-Ruiz, Ricardo, Heyndrickx, Guy R., Nyolczas, Noémi, Legrand, Victor, Guédès, Antoine, Heyse, Alex, Moccetti, Tiziano, Fernandez-Aviles, Francisco, Jimenez-Quevedo, Pilar, Bayes-Genis, Antoni, Hernandez-Garcia, Jose Maria, Ribichini, Flavio, Gruchala, Marcin, Waldman, Scott A., Teerlink, John R., Gersh, Bernard J., Povsic, Thomas J., Henry, Timothy D., Metra, Marco, Hajjar, Roger J., Tendera, Michal, Behfar, Atta, Alexandre, Bertrand, Seron, Aymeric, Stough, Wendy Gattis, Sherman, Warren, Cotter, Gad, Wijns, William
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Fast-Track Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381596/
https://ncbi.nlm.nih.gov/pubmed/28025189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehw543
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