Stimulation of astrocyte fatty acid oxidation by thyroid hormone is protective against ischemic stroke-induced damage

We previously demonstrated that stimulation of astrocyte mitochondrial ATP production via P2Y(1) receptor agonists was neuroprotective after cerebral ischemic stroke. Another mechanism that increases ATP production is fatty acid oxidation (FAO). We show that in primary human astrocytes, FAO and ATP...

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Publicado en:J Cereb Blood Flow Metab
Autores principales: Sayre, Naomi L, Sifuentes, Mikaela, Holstein, Deborah, Cheng, Sheue-yann, Zhu, Xuguang, Lechleiter, James D
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2016
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381439/
https://ncbi.nlm.nih.gov/pubmed/26873887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16629153
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