Use of a tuberculin purified protein derivative--Asn-Ala-Asn-Pro conjugate in bacillus Calmette-Guérin primed mice overcomes H-2 restriction of the antibody response and avoids the need for adjuvants.

Because of its immunodominancy, and because it is conserved in different geographical isolates of Plasmodium falciparum, the repetitive sequence of the circumsporozoite protein, (Asn-Ala-Asn-Pro)n [(NANP)n], has been envisaged for the development of an anti-falciparum malaria subunit vaccine. Howeve...

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Detalhes bibliográficos
Main Authors: Lussow, A R, Del Giudice, G, Rénia, L, Mazier, D, Verhave, J P, Verdini, A S, Pessi, A, Louis, J A, Lambert, P H
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53813/
https://ncbi.nlm.nih.gov/pubmed/2183219
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