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Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes
Chronic inflammation plays a key role in both type 1 and type 2 diabetes. Cytokine and chemokine production within the islets in a diabetic milieu results in β-cell failure and diabetes progression. Identification of targets, which both prevent macrophage activation and infiltration into islets and...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5381285/ https://ncbi.nlm.nih.gov/pubmed/28378743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45319 |
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