Independent strong association of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvement

Stevens-Johnson syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin and mucous membranes. Cold medicines including non-steroidal anti-inflammatory drugs (NSAIDs) and multi-ingredient cold medications are reported to be...

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Publicado no:Sci Rep
Main Authors: Ueta, Mayumi, Kaniwa, Nahoko, Sotozono, Chie, Tokunaga, Katsushi, Saito, Yoshiro, Sawai, Hiromi, Miyadera, Hiroko, Sugiyama, Emiko, Maekawa, Keiko, Nakamura, Ryosuke, Nagato, Masaki, Aihara, Michiko, Matsunaga, Kayoko, Takahashi, Yukitoshi, Furuya, Hirokazu, Muramatsu, Masaaki, Ikezawa, Zenrou, Kinoshita, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381277/
https://ncbi.nlm.nih.gov/pubmed/24781922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04862
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