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Chitosan-Zein Nano-in-Microparticles Capable of Mediating In Vivo Transgene Expression Following Oral Delivery

The oral route is an attractive delivery route for the administration of DNA-based therapeutics, specifically for applications in gene therapy and DNA vaccination. However, oral DNA delivery is complicated by the harsh and variable conditions encountered throughout gastrointestinal (GI) transit, lea...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Farris, Eric, Brown, Deborah M., Ramer-Tait, Amanda E., Pannier, Angela K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380973/
https://ncbi.nlm.nih.gov/pubmed/28153762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.01.035
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