Alpha-lipoic acid ameliorates the epithelial mesenchymal transition induced by unilateral ureteral obstruction in mice

The epithelial-to-mesenchymal transition (EMT) is one of mechanisms that induce renal interstitial fibrosis. Understanding EMT in renal fibrosis has important therapeutic implications for patients with kidney disease. Alpha-lipoic acid (ALA) is a natural compound with antioxidant properties. Studies...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Cho, Hyun Seop, Kim, Jin Hyun, Jang, Ha Nee, Lee, Tae Won, Jung, Myeong Hee, Kim, Tae Ho, Chang, Se-Ho, Park, Dong Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380949/
https://ncbi.nlm.nih.gov/pubmed/28378840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46065
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