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Interferon gamma boosts the nucleotide oligomerization domain 2-mediated signaling pathway in human dendritic cells in an X-linked inhibitor of apoptosis protein and mammalian target of rapamycin-dependent manner

The cytoplasmic nucleotide oligomerization domain 2 (NOD2) receptor recognizes the bacterial cell wall component muramyl dipeptide (MDP). NOD2 ligation initiates the nuclear factor kappa B and the mitogen-activated protein kinase cascades. However, administering MDP alone is insufficient to elicit s...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Fekete, Tünde, Koncz, Gabor, Szabo, Brigitta, Gregus, Andrea, Rajnavölgyi, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380943/
https://ncbi.nlm.nih.gov/pubmed/26521691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.90
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