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Revisiting Seed and Soil: Examining the Primary Tumor and Cancer Cell Foraging in Metastasis

Metastasis is the consequence of a cancer cell that disperses from the primary tumor, travels throughout the body, and invades and colonizes a distant site. Based on Paget’s 1889 hypothesis, the majority of modern metastasis research focuses on the properties of the metastatic “seed and soil,” but t...

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Veröffentlicht in:Mol Cancer Res
Hauptverfasser: de Groot, Amber E., Roy, Sounak, Brown, Joel S., Pienta, Kenneth J., Amend, Sarah R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380470/
https://ncbi.nlm.nih.gov/pubmed/28209759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0436
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