B vitamins attenuate the epigenetic effects of ambient fine particles in a pilot human intervention trial

Acute exposure to fine particle (PM(2.5)) induces DNA methylation changes implicated in inflammation and oxidative stress. We conducted a crossover trial to determine whether B-vitamin supplementation averts such changes. Ten healthy adults blindly received a 2-h, controlled-exposure experiment to s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhong, Jia, Karlsson, Oskar, Wang, Guan, Li, Jun, Guo, Yichen, Lin, Xinyi, Zemplenyi, Michele, Sanchez-Guerra, Marco, Trevisi, Letizia, Urch, Bruce, Speck, Mary, Liang, Liming, Coull, Brent A., Koutrakis, Petros, Silverman, Frances, Gold, Diane R., Wu, Tangchun, Baccarelli, Andrea A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380085/
https://ncbi.nlm.nih.gov/pubmed/28289216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618545114
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