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Enhancing Paradynamics for QM/MM Sampling of Enzymatic Reactions

Despite the enormous increase in computer power, it is still extremely challenging to obtain computationally converging sampling of ab initio QM/MM (QM(ai)/MM) free energy surfaces in condensed phases. The sampling problem can be significantly reduced by the use of the reference potential paradynami...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Phys Chem B
Egile Nagusiak: Lameira, Jerônimo, Kupchencko, Ilya, Warshel, Arieh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380004/
https://ncbi.nlm.nih.gov/pubmed/26866994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b11966
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