The germline variants in DNA repair genes in pediatric medulloblastoma: a challenge for current therapeutic strategies

BACKGROUND: The defects in DNA repair genes are potentially linked to development and response to therapy in medulloblastoma. Therefore the purpose of this study was to establish the spectrum and frequency of germline variants in selected DNA repair genes and their impact on response to chemotherapy...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Trubicka, Joanna, Żemojtel, Tomasz, Hecht, Jochen, Falana, Katarzyna, Piekutowska- Abramczuk, Dorota, Płoski, Rafał, Perek-Polnik, Marta, Drogosiewicz, Monika, Grajkowska, Wiesława, Ciara, Elżbieta, Moszczyńska, Elżbieta, Dembowska-Bagińska, Bożenna, Perek, Danuta, Chrzanowska, Krystyna H., Krajewska-Walasek, Małgorzata, Łastowska, Maria
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379555/
https://ncbi.nlm.nih.gov/pubmed/28376765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3211-y
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