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Molecular cloning of mevalonate kinase and regulation of its mRNA levels in rat liver.

Mevalonate kinase [ATP:(R)-mevalonate 5-phosphotransferase, EC 2.7.1.36] may be a regulatory site in the cholesterol biosynthetic pathway, and a mutation in the gene coding for this enzyme is thought to cause the genetic disease mevalonic aciduria. To characterize this enzyme, a rat liver cDNA libra...

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Detalhes bibliográficos
Main Authors: Tanaka, R D, Lee, L Y, Schafer, B L, Kratunis, V J, Mohler, W A, Robinson, G W, Mosley, S T
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53795/
https://ncbi.nlm.nih.gov/pubmed/2158094
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