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Resveratrol protects podocytes against apoptosis via stimulation of autophagy in a mouse model of diabetic nephropathy

Podocyte apoptosis coincides with albuminuria onset and precedes podocytopenia in diabetic nephropathy. However, there is a lack of effective therapeutic drugs to protect podocytes from apoptosis. Here, we demonstrated that resveratrol relieved a series of indicators of diabetic nephropathy and atte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Huang, Shan-Shan, Ding, Da-Fa, Chen, Sheng, Dong, Cheng-Long, Ye, Xiao-Long, Yuan, Yang-Gang, Feng, Ya-Min, You, Na, Xu, Jia-Rong, Miao, Heng, You, Qiang, Lu, Xiang, Lu, Yi-Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379482/
https://ncbi.nlm.nih.gov/pubmed/28374806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45692
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