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Cultured 3T3L1 adipocytes dispose of excess medium glucose as lactate under abundant oxygen availability

White adipose tissue (WAT) produces lactate in significant amount from circulating glucose, especially in obesity;Under normoxia, 3T3L1 cells secrete large quantities of lactate to the medium, again at the expense of glucose and proportionally to its levels. Most of the glucose was converted to lact...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sabater, David, Arriarán, Sofía, Romero, María del Mar, Agnelli, Silvia, Remesar, Xavier, Fernández-López, José Antonio, Alemany, Marià
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379156/
https://ncbi.nlm.nih.gov/pubmed/24413028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03663
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