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Quasi-elastic neutron scattering reveals ligand-induced protein dynamics of a G-protein–coupled receptor
Light activation of the visual G-protein-coupled receptor rhodopsin leads to significant structural fluctuations of the protein embedded within the membrane. Enhancement of protein dynamics upon stimulation of the GPCR yields activation of the cognate G-protein (transducin) that initiates biological...
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| Publicado no: | J Phys Chem Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378701/ https://ncbi.nlm.nih.gov/pubmed/27628201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.6b01632 |
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