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Neoadjuvant oncogene-targeted therapy in early stage non-small cell lung cancer as a strategy to improve clinical outcome and identify early mechanisms of resistance

Evaluations of resistance mechanisms to targeted treatments in non-small cell lung cancer (NSCLC) are necessary for development of improved treatment after progression and to help delay progression. Populations of cells that survive after initial treatment form the basis of resistance via outgrowth...

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Опубликовано в: :Clin Lung Cancer
Главные авторы: McCoach, Caroline E., Bivona, Trever G., Blakely, Collin M., Doebele, Robert C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378381/
https://ncbi.nlm.nih.gov/pubmed/27378174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cllc.2016.05.025
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