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Imaging PEG-like Nanoprobes in Tumor, Transient Ischemia and Inflammatory Disease Models

The iron chelator deferoxamine (DFO), approved for the treatment of iron overload, has been examined as a therapeutic in a variety of conditions which iron may exacerbate. To evaluate the potential of DFO-bearing PEG-like Nanoprobes (DFO-PNs) as therapeutics, we determined their pharmacokinetics (PK...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Wilks, Moses Q., Normandin, Marc D., Yuan, Hushan, Cho, Hoonsung, Guo, Yanyan, Herisson, Fanny, Ayata, Cenk, Wooten, Dustin W., El Fakhri, Georges, Josephson, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378316/
https://ncbi.nlm.nih.gov/pubmed/25971846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00213
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