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Targeting human vasohibin‐2 by a neutralizing monoclonal antibody for anti‐cancer treatment

There are two members of the vasohibin (VASH) family, VASH1 and VASH2. VASH1 is expressed mainly in endothelial cells to inhibit angiogenesis, whereas VASH2 is expressed mainly in cancer cells to stimulate tumor growth. The aim of the present study was to establish neutralizing monoclonal antibody (...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Koyanagi, Takahiro, Suzuki, Yasuhiro, Komori, Kazuki, Saga, Yasushi, Matsubara, Shigeki, Fujiwara, Hiroyuki, Sato, Yasufumi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378258/
https://ncbi.nlm.nih.gov/pubmed/28032401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13149
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