Transcriptome analyses of rhesus monkey preimplantation embryos reveal a reduced capacity for DNA double-strand break repair in primate oocytes and early embryos

Preimplantation embryogenesis encompasses several critical events including genome reprogramming, zygotic genome activation (ZGA), and cell-fate commitment. The molecular basis of these processes remains obscure in primates in which there is a high rate of embryo wastage. Thus, understanding the fac...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Wang, Xinyi, Liu, Denghui, He, Dajian, Suo, Shengbao, Xia, Xian, He, Xiechao, Han, Jing-Dong J., Zheng, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378175/
https://ncbi.nlm.nih.gov/pubmed/28223401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.198044.115
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