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HIV BROADLY NEUTRALIZING ANTIBODIES: TAKING GOOD CARE OF THE 98%

In this issue of Immunity, Huang et al. describe an exceptionally broad and potent neutralizing antibody to HIV. This antibody, N6, is capable of neutralizing up to 98% of global isolates with a potent median IC(50) of 0.04 μg/ml, making it the current “best-in-class” for bnAbs targeting the CD4 bin...

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Enregistré dans:
Détails bibliographiques
Publié dans:Immunity
Auteurs principaux: Sok, Devin, Burton, Dennis R.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378060/
https://ncbi.nlm.nih.gov/pubmed/27851923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.10.033
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