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Diverse Phenotypic Expression of Cardiomyopathies in a Family with TNNI3 p.Arg145Trp Mutation

Genetic diagnosis of cardiomyopathies is challenging, due to the marked genetic and allelic heterogeneity and the lack of knowledge of the mutations that lead to clinical phenotypes. Here, we present the case of a large family, in which a single TNNI3 mutation caused variable phenotypic expression,...

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Detalhes bibliográficos
Publicado no:Korean Circ J
Main Authors: Hwang, Ji-won, Jang, Mi-Ae, Jang, Shin Yi, Seo, Soo Hyun, Seong, Moon-Woo, Park, Sung Sup, Ki, Chang-Seok, Kim, Duk-Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Cardiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378035/
https://ncbi.nlm.nih.gov/pubmed/28382084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4070/kcj.2016.0213
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