Extracellular Vesicle-functionalized Decalcified Bone Matrix Scaffolds with Enhanced Pro-angiogenic and Pro-bone Regeneration Activities

Vascularization is crucial for bone regeneration after the transplantation of tissue-engineered bone grafts in the clinical setting. Growing evidence suggests that mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) are potently pro-angiogenic both in vitro and in vivo. In the current s...

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Udgivet i:Sci Rep
Main Authors: Xie, Hui, Wang, Zhenxing, Zhang, Liming, Lei, Qian, Zhao, Aiqi, Wang, Hongxiang, Li, Qiubai, Cao, Yilin, Jie Zhang, Wen, Chen, Zhichao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377422/
https://ncbi.nlm.nih.gov/pubmed/28367979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45622
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